Within the investing sport, it’s not solely about what you purchase; it’s about if you purchase it. One of the vital widespread items of recommendation thrown across the Road, “purchase low” is touted as a tried-and-true tactic.Positive, the technique appears easy. Inventory costs naturally fluctuate on the premise of a number of elements like earnings outcomes and the macro setting, amongst others, with buyers making an attempt to time the market and decide when shares have hit a backside. In apply, nevertheless, executing on this technique is not any simple process.On high of this, given the volatility that has dominated the markets over the previous couple of weeks, how are buyers presupposed to gauge when a reputation is flirting with a backside? That’s the place the Wall Road execs are available in.These skilled inventory pickers have recognized three compelling tickers whose present share costs land near their 52-week lows. Noting that every is ready to take again off on an upward trajectory, the analysts see a beautiful entry level. Utilizing TipRanks’ database, we came upon that the analyst consensus has rated all three a Robust Purchase, with main upside potential additionally on faucet.Progenity (PROG)Providing clear and actionable genetic outcomes, Progenity focuses on offering testing providers. The corporate began buying and selling on Nasdaq in June and noticed its shares tumbling 44% since then. With shares altering arms for $eight.11, a number of members of the Road advocate pulling the set off earlier than it heats up.Piper Sandler analyst Steven Mah factors out that even in opposition to the backdrop of COVID-19, PROG managed to ship with its Q2 2020 efficiency. “We’re inspired by the restoration in late Q2 2020 with 75,000 accessioned exams (~79,000 in Q1 2020), pushed by noninvasive prenatal testing (NIPT) and provider screening,” the analyst famous. Expounding on this, Mah acknowledged, “Progenity didn’t present steering, however June check volumes of ~28,000 have been robust (Q1 2020 month-to-month common was ~26,000) which we imagine showcases the sturdiness of its reproductive exams and the success that Progenity has in co-marketing and attaching provider screening to the extra important NIPT. Of be aware, regardless of the pandemic disruptions, Progenity was capable of keep its main pre-COVID check turnaround occasions.”Moreover, well being insurer Aetna is briefly extending protection of average-risk NIPT till year-end because of the pandemic, with the American School of Obstetricians and Gynecologists (ACOG) additionally anticipated to endorse average-risk sooner or later given its scientific utility, in Mah’s opinion.Reflecting one other optimistic, the fourth technology NIPT (single-molecule counting assay) check was capable of measure fetal fraction, a key milestone based on Mah, and can proceed to be developed into 2021. Because the know-how might probably be utilized to DNA, RNA, epigenetic markers and proteins for added scientific purposes reminiscent of oncology, the analyst is trying ahead to the completion of the preeclampsia verification in This fall 2020 and a attainable 2H21 launch. “We imagine preeclampsia (~2.three billion serviceable market) is a significant differentiator for Progenity, permitting them to cross-sell throughout the full-continuum of reproductive testing,” the analyst added.If that wasn’t sufficient, PROG signed its first GI Precision Drugs partnership settlement with a top-20 Pharma firm in August. The Oral Biotherapeutic Supply System (OBDS), an ingestible drug and system mixture designed to exactly ship biologics systemically by a needle-free liquid jet injection into the submucosal tissues of the small gut, is ready to be utilized as a part of the collaboration. Mah commented, “We imagine Progenity can signal further Pharma offers and stay up for the newsflow popping out on this entrance.”To sum all of it up, Mah mentioned, “We imagine Progenity shares are undervalued given the sturdy restoration within the core testing enterprise and a number of upcoming progress catalysts.”To this finish, Mah charges PROG an Obese (i.e. Purchase) together with a $17 worth goal. Ought to his thesis play out, a twelve-month achieve of 105% might probably be within the playing cards. (To observe Mah’s monitor file, click on right here)Are different analysts in settlement? They’re. Solely Purchase scores, four, the truth is, have been issued within the final three months. Subsequently, the message is evident: PROG is a Robust Purchase. Given the $13.33 common worth goal, shares might climb 60% larger within the subsequent yr. (See PROG inventory evaluation on TipRanks)Tactile Techniques Know-how (TCMD)Creating at-home remedy units, Tactile Techniques Know-how needs to offer new therapies for lymphedema, which happens when the lymphatic system is impaired, disrupting regular transport of fluid inside the physique, and continual venous insufficiency. Down 52% year-to-date, its $32.67 share worth lands near its $29.47 52-week low. Thus, with enterprise developments bettering, the Road is pounding the desk.Writing for Canaccord, analyst Cecilia Furlong acknowledges that the pandemic has hampered the corporate, with COVID-19 weighing on each volumes and gross sales. Within the second half of March, volumes have been down 50% in comparison with the primary half of the month, and TCMD’s affected person volumes in April and Could remained challenged. That being mentioned, developments began to enhance on the finish of Could.“Going ahead, given the overwhelming majority of TCMD’s clinician prospects apply in outpatient or office-based settings, we stay optimistic on TCMD’s skill to display higher insulation in opposition to COVID impacts and sure expertise a larger bounce-back relative to total med-tech quantity developments, with TCMD additional benefitting from its increasing utilizing of know-how to remotely have interaction with clinicians and assist sufferers,” Furlong defined.The analyst added, “Moreover, latest developments amongst some suppliers to prescribe Flexitouch (a sophisticated intermittent pneumatic compression system to self-manage lymphedema and nonhealing venous leg ulcers) earlier alongside the remedy course of, as a way to scale back in-person contact, might present upside close to time period, in addition to probably transition to a longer-term tailwind.”On high of this, Furlong can also be optimistic about new CEO Dan Reuvers and the reprioritization of the corporate’s funding and market improvement efforts. TCMD will shift focus away from its acquired Airwear product line, with it redirecting investments towards its Flexitouch and Entre (a pneumatic compression system used to help within the dwelling administration of continual swelling and venous ulcers related to lymphedema and continual venous insufficiency) merchandise.“Given vital under-penetration within the lymphedema/phlebolymphedema market focused by Flexitouch alongside the massive affected person inhabitants with restricted remedy choices right now focused by the agency’s Head & Neck platform, we view the mix of schooling and scientific information as key to additional growing and penetrating these markets… Going ahead, we anticipate administration to proceed to compile a broad base of scientific information to assist reimbursement and drive broad adoption,” Furlong commented.All of this prompted Furlong to maintain a Purchase ranking and $62 worth goal on the inventory. This goal conveys her confidence in TCMD’s skill to soar 90% within the subsequent yr. (To observe Furlong’s monitor file, click on right here)Normally, different analysts are on the identical web page. With three Purchase scores and 1 Maintain, the phrase on the Road is that TCMD is a Robust Purchase. The $62.33 common worth goal brings the upside potential to 91%. (See TCMD inventory evaluation on TipRanks)uniQure N.V. (QURE)Final however not least we’ve got uniQure, which delivers healing gene therapies that would probably rework the lives of sufferers. Though shares have fallen 44% year-to-date to $40, not a lot larger than its 52-week low of $36.20, a number of analysts nonetheless have excessive hopes.Representing SVB Leerink, 5-star analyst Joseph Schwartz acknowledges that shares struggled after information broke of its collaboration and licensing settlement with CSL Behring for AMT-061, QURE’s gene remedy for Hemophilia B, he argues the “shareholder base turnover is probably going now full as buyers and QURE shift focus to next-in-line AMT-130, its AAV5 gene remedy for Huntington’s Illness (HD).”Schwartz additional added, “With the M&A premium now out of the inventory, we see the QURE’s present stage as a beautiful shopping for alternative for these buyers within the firm’s up and coming CNS gene therapies, inner manufacturing, and sturdy mental property and knowhow.”Wanting extra intently on the settlement with CSL Behring, QURE can be tasked with the completion of the pivotal Section three HOPE-B trial in addition to the manufacturing course of validation and manufacturing provide of AMT-061.In keeping with administration, 26-week Issue IX (FIX) information from all 54 sufferers enrolled within the trial stays on monitor, and topline information from the pivotal trial continues to be slated to learn out by YE20. It ought to be talked about that in a Section 2b dose-confirmation research, QURE reported 41% FIX exercise out to at least one yr. Moreover, Schwartz factors out that with HOPE-B progressing as deliberate, QURE has continued its manufacturing course of validation work forward of the anticipated BLA/MAA submissions within the U.S. and EU in 2021.On high of this, as a part of the deal, QURE is eligible to obtain greater than $2 billion together with a $450 million upfront money fee, $1.6 billion in regulatory and business milestones and double-digit royalties ranging as much as the low-twenties proportion of internet product gross sales.“With a strengthened money place, QURE is nicely funded to quickly advance CNS belongings together with AMT-130 (AAV5 gene remedy for Huntington’s Illness (HD)) and AMT-150 (AAV gene remedy for Spinocerebellar Ataxia Kind three/SCA3)…We proceed to imagine that as QURE’s CNS pipeline belongings mature, the corporate might as soon as once more be a beautiful associate to bigger biopharma firms which have not too long ago acquired many publicly traded gene remedy platforms with substantial manufacturing capabilities,” Schwartz famous.Every thing that QURE has going for it satisfied Schwartz to reiterate an Outperform (i.e. Purchase) ranking. Together with the decision, he hooked up a $67 worth goal, suggesting 68% upside potential from present ranges. (To observe Schwartz’s monitor file, click on right here)What does the remainder of the Road must say? 9 Buys and three Holds have been issued within the final three months, so the consensus ranking is a Robust Purchase. As well as, the $69.89 common worth goal signifies 75% upside potential. (See QURE inventory evaluation on TipRanks)To search out good concepts for beaten-down shares buying and selling at enticing valuations, go to TipRanks’ Greatest Shares to Purchase, a newly launched device that unites all of TipRanks’ fairness insights.Disclaimer: The opinions expressed on this article are solely these of the featured analysts. The content material is meant for use for informational functions solely. It is extremely vital to do your personal evaluation earlier than making any funding.